Anti-HOXA4 Antibody Picoband® Fluoro488 Conjugated

HOXA4 (HOMEOBOX A4), also known as HOX1D or HOMOLOG OF, is a protein that in humans is encoded by the HOXA4 gene, which is also part of the A cluster on chromosome 7. HOXA4 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.

A synthetic peptide corresponding to a sequence in the middle region of human HOXA4, which shares 72.2% and 61.1% amino acid (aa) sequence identity with mouse and rat HOXA4, respectively.

Mainly expressed in testis. Expressed to a lower level in thymus. Weakly or not expressed in heart, liver, brain, placenta, lung, skeletal muscle, kidney and pancreas.

Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Oxidative Stress, Pathways and Processes, Redox Metabolism, Signal Transduction

1. McAlpine PJ, Shows TB (July 1990) . Nomenclature for human homeobox genes. 2. Scott MP (November 1992) . Vertebrate homeobox gene nomenclature. 3. Entrez Gene: HOXA4 homeobox A4.