Anti-Septin 8/Septin8 Antibody Picoband® Fluoro647 Conjugated

Predicted to enable GTPase activity; SNARE binding activity; and molecular adaptor activity. Predicted to be involved in several processes, including regulation of SNARE complex assembly; regulation of intracellular protein transport; and regulation of protein stability. Located in myelin sheath. Part of septin complex. Is expressed in dermis; spinal cord ventricular layer; turbinate bone primordium; and ventral grey horn. Orthologous to human Septin8 (septin 8) .

A synthetic peptide corresponding to a sequence at the C-terminus of mouse Septin 8/Septin8, which shares 95.7% and 100% amino acid (aa) sequence identity with human and rat SEPTIN8, respectively.

1. Blaser, S., Jersch, K., Hainmann, I., Wunderle, D., Zgaga-Griesz, A., Busse, A., Zieger, B. Human septin-septin interaction: CDCrel-1 partners with KIAA0202. FEBS Lett. 519: 169-172, 2002. 2. Blaser, S., Jersch, K., Hainmann, I., Zieger, W., Wunderle, D., Busse, A., Zieger, B. Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202) . Gene 312: 313-320, 2003. 3. Nagase, T., Seki, N., Ishikawa, K., Ohira, M., Kawarabayasi, Y., Ohara, O., Tanaka, A., Kotani, H., Miyajima, N., Nomura, N. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 3: 321-329, 1996.