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Anti-KLF13 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Kruppel-like factor 13, also known as KLF13, is a protein that in humans is encoded by the KLF13 gene. KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif) . These transcription factors bind to GC-rich sequences and related GT and CACCC boxes.

Synonyms

Ribosome-binding protein 1; 180 kDa ribosome receptor homolog; RRp; ES/130-related protein; Ribosome receptor protein; RRBP1; KIAA1398

Gene Name

KLF13

Gene ID

51621

UniProt

Q9Y2Y9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human KLF13 recombinant protein (Position: K56-R260) .

Clonality

Polyclonal

Tissue Specificity

Expressed in kidney.

Applications

Flow Cytometry

Field of Research

Cancer, DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, Translation, Tumor Biomarkers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.

References & Citations

1. Asano, H., Li, X. S., Stamatoyannopoulos, G. FKLF-2: a novel Kruppel-like transcriptional factor that activates globin and other erythroid lineage genes. Blood 95: 3578-3584, 2000. 2. Scohy, S., Gabant, P., Van Reeth, T., Hertveldt, V., Dreze, P.-L., Van Vooren, P., Riviere, M., Szpirer, J., Szpiper, C. Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family. Genomics 70: 93-101, 2000. 3. Scott, A. F. Personal Communication. Baltimore, Md. 9/25/2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Ribosome binding protein 1

Subcellular Location

Endoplasmic reticulum membrane, Single-pass type III membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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