Anti-MIPOL1 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
MIPOL1 (Mirror Image Polydactyly 1), also known as CCDC193 (Coiled-coil domain containing 193), is a protein that in humans is encoded by the MIPOL1 gene. This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described.
Synonyms
Solute carrier family 2, facilitated glucose transporter member 6; Glucose transporter type 6; GLUT-6; Glucose transporter type 9; GLUT-9; SLC2A6; GLUT9
Gene Name
MIPOL1
Gene ID
145282
UniProt
Q8TD10
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human MIPOL1 recombinant protein (Position: N63-A399) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain, spleen and peripheral blood leukocytes.
Applications
Flow Cytometry
Field of Research
Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
Facilitative glucose transporter; binds cytochalasin B with low affinity.
References & Citations
1. Kamnasaran, D., O'Brien, P. C., Zackai, E. H., Muenke, M., Ferguson-Smith, M. A., Cox, D. W. Rearrangement in the PITX2 and MIOL1 genes in a patient with a t (4;14) chromosome. Europ. J. Hum. Genet. 11: 315-324, 2003. 2. Kondoh, S., Sugawara, H., Harada, N., Matsumoto, N., Ohashi, H., Sato, M., Kantaputra, P. N., Ogino, T., Tomita, H., Ohta, T., Kishino, T., Fukushima, Y., Niikawa, N., Yoshiura, K. A novel gene is disrupted at a 14q13 breakpoint of t (2;14) in a patient with mirror-image polydactyly of hands and feet. J. Hum. Genet. 47: 136-139, 2002.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Solute carrier family 2 member 6
Subcellular Location
Cell membrane. Multi-pass membrane protein.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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