Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-KMO Antibody Picoband®

Boster Bio Anti-KMO Antibody Picoband® catalog # A05469-3. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Kynurenine 3-monooxygenase is an enzyme that in humans is encoded by the KMO gene. This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease.

Synonyms

Prion-like protein doppel; PrPLP; Prion protein 2; PRND; DPL; UNQ1830/PRO3443

Gene Name

KMO

Gene ID

8564

UniProt

O15229

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human KMO recombinant protein (Position: F26-N372) .

Clonality

Polyclonal

Tissue Specificity

Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level) .

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Neurodegenerative Disease, Neurology Process, Neuroscience

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Required for normal acrosome reaction and for normal male fertility (By similarity) . Can bind Cu (2+) (PubMed:15218028, PubMed:20411530) .

References & Citations

1. Alberati-Giani, D., Cesura, A. M., Broger, C., Warren, W. D., Rover, S., Malherbe, P. Cloning and functional expression of human kynurenine 3-monooxygenase. FEBS Lett. 410: 407-412, 1997. 、 2. Giorgini, F., Guidetti, P., Nguyen, Q., Bennett, S. C., Muchowski, P. J. A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease. Nature Genet. 37: 526-536, 2005. 3. Halford, S., Freedman, M. S., Bellingham, J., Inglis, S. L., Poopalasundaram, S., Soni, B. G., Foster, R. G., Hunt, D. M. Characterization of a novel human opsin gene with wide tissue expression and identification of embedded and flanking genes on chromosome 1q43. Genomics 72: 203-208, 2001.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

39411 MW

Observed Molecular Weight

50 kDa

Applications Notes

6

Gene Name Synonym

Prion like protein doppel

Subcellular Location

Cell membrane.

Protein Name

Zinc finger protein Helios

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal Orai1 Antibody (6D11A11) [mFluor Violet 500 SE]
NBP1-75523MFV500 0.1 mL

Mouse Monoclonal Orai1 Antibody (6D11A11) [mFluor Violet 500 SE]

Ask
View Details
DNAJC25 Antibody
E51A13045 100 µL

DNAJC25 Antibody

Ask
View Details
Lentiviral human NUP210 sgRNA gene knockout kit - Lentiviral human NUP210 sgRNA gene knockout kit (plasmid)
GTR15377501 1 Vial

Lentiviral human NUP210 sgRNA gene knockout kit - Lentiviral human NUP210 sgRNA gene knockout kit (plasmid)

Ask
View Details
Human IgG3 Recombinant Antibody, PE-Cy5.5 Conjugated
bsm-61621R-PE-Cy5.5 100 µL

Human IgG3 Recombinant Antibody, PE-Cy5.5 Conjugated

Ask
View Details
Gliomedin shRNA (m) Lentiviral Particles
sc-62379-V 200 µL

Gliomedin shRNA (m) Lentiviral Particles

Ask
View Details
FBXO33 Human Gene Knockout Kit (CRISPR)
KN408823 1 Kit

FBXO33 Human Gene Knockout Kit (CRISPR)

Ask
View Details