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Anti-HCLS1 Antibody Picoband®

Boster Bio Anti-HCLS1 Antibody Picoband® catalog # A04313-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Hematopoietic lineage cell-specific protein is a protein that in humans is encoded by the HCLS1 gene. Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of transcription, DNA-templated. Located in cytosol; nucleus; and plasma membrane. Part of transcription regulator complex.

Synonyms

Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; CD123; IL3RA; IL3R

Gene Name

HCLS1

Gene ID

3059

UniProt

P14317

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human HCLS1 recombinant protein (Position: N213-K473) .

Clonality

Polyclonal

Tissue Specificity

Brain.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

This is a receptor for interleukin-3.

References & Citations

1. Egashira, M., Kitamura, D., Watanabe, T., Niikawa, N. The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization. Cytogenet. Cell Genet. 72: 175-176, 1996. 2. Kitamura, D., Kaneko, H., Miyagoe, Y., Ariyasu, T., Watanabe, T. Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage. Nucleic Acids Res. 17: 9367-9379, 1989. 3. Scielzo, C., Ghia, P., Conti, A., Bachi, A., Guida, G., Geuna, M., Alessio, M., Caligaris-Cappio, F. HS1 protein is differentially expressed in chronic lymphocytic leukemia patient subsets with good or poor prognoses. J. Clin. Invest. 115: 1644-1650, 2005.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04313-1

Product MSDS

https://www.bosterbio.com/msds?sku=A04313-1

Observed Molecular Weight

75 kDa

Applications Notes

6

Gene Name Synonym

Interleukin 3 receptor subunit alpha

Subcellular Location

Membrane. Single-pass type I membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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