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Anti-CD64/FCGR1A Antibody Picoband®

Boster Bio Anti-CD64/FCGR1A Antibody Picoband® catalog # A02428-3. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

High affinity immunoglobulin gamma Fc receptor I is a protein that in humans is encoded by the FCGR1A gene. It is mapped to 1q21.2. This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.

Synonyms

High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD64; FCGR1A; FCG1; FCGR1; IGFR1

Gene Name

FCGR1A

Gene ID

2209

UniProt

P12314

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human CD64/FCGR1A recombinant protein (Position: A191-D254) .

Clonality

Polyclonal

Tissue Specificity

Monocyte/macrophage specific.

Applications

ELISA, Flow Cytometry, WB

Field of Research

Immunoglobulins, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

References & Citations

1. Entrez Gene: FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) . 2. Maresco DL, Blue LE, Culley LL, Kimberly RP, Anderson CL, Theil KS (November 1998) . Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1. Cytogenetics and Cell Genetics. 82 (1-2) : 71–4. 3. van de Winkel JG, Ernst LK, Anderson CL, Chiu IM (Jul 1991) . Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64) . Characterization and evidence for a second gene.The Journal of Biological Chemistry. 266 (20) : 13449–55.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

38779 MW

Observed Molecular Weight

70 kDa

Applications Notes

6

Gene Name Synonym

Fc fragment of IgG receptor Ia

Subcellular Location

Cell membrane.

Protein Name

BAG family molecular chaperone regulator 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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