Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-BST2/Tetherin Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Tetherin, also known as bone marrow stromal antigen 2, is a lipid raft associated protein that in humans is encoded by the BST2 gene. Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.

Synonyms

Tafazzin; Protein G4.5; TAZ; EFE2, G4.5

Gene Name

BST2

Gene ID

684

UniProt

Q10589

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human BST2/Tetherin recombinant protein (Position: N49-S161) .

Clonality

Polyclonal

Tissue Specificity

High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.

Applications

Flow Cytometry

Field of Research

Cancer, Cardiogenesis, Cardiovascular, Domain Families, Epigenetics and Nuclear Signaling, Oncoproteins, Oncoproteins/Suppressors, Transcription, Transcription Factors, Transcription Factors/Regulators

Purification

Immunogen affinity purified.

Form

Liquid

Function

Some isoforms may be involved in cardiolipin (CL) metabolism.

References & Citations

1. Cocka, L. J., Bates, P. Identification of alternatively translated tetherin isoforms with differing antiviral and signaling activities. PLoS Pathog. 8: e1002931, 2012. Note: Electronic Article. 2. Ishikawa, J., Kaisho, T., Tomizawa, H., Lee, B. O., Kobune, Y., Inazawa, J., Oritani, K., Itoh, M., Ochi, T., Ishihara, K., Hirano, T. Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth. Genomics 26: 527-534, 1995. 3. Kuhl, A., Munch, J., Sauter, D., Bertram, S., Glowacka, I., Steffen, I., Sprecht, A., Hofmann, H., Schneider, H., Behrens, G., Pohlmann, S. Calcium-modulating cyclophilin ligand does not restrict retrovirus release. (Letter) Nature Med. 16: 155-157, 2010.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

50408 MW

Applications Notes

6

Gene Name Synonym

Tafazzin

Subcellular Location

Cytoplasm . Nucleus . Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27. .

Protein Name

Protein C-ets-1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Fbxl6 (NM_013909) Mouse Tagged Lenti ORF Clone
MR219101L4 10 µg

Fbxl6 (NM_013909) Mouse Tagged Lenti ORF Clone

Ask
View Details
Rabbit Monoclonal Cystatin E/M/CST6 Antibody (022) [DyLight 405]
NBP2-89499V 0.1 mL

Rabbit Monoclonal Cystatin E/M/CST6 Antibody (022) [DyLight 405]

Ask
View Details
Porcine PTHrP (Parathyroid Hormone Related Protein) ValidElisa Kit
EK344741 96 Well

Porcine PTHrP (Parathyroid Hormone Related Protein) ValidElisa Kit

Ask
View Details
Human EGFEM1P ELISA KIT
ELI-32258h 96 Tests

Human EGFEM1P ELISA KIT

Ask
View Details
Rat Psd3 Pre-designed siRNA Set A
SI211226A 1 Each

Rat Psd3 Pre-designed siRNA Set A

Ask
View Details
NKX2-5 (NK2 Transcription Factor Related, locus 5 (Drosophila), CHNG5, CSX, CSX1, NKX2.5, NKX2E, NKX4-1) (APC)
249336-APC 100 µL

NKX2-5 (NK2 Transcription Factor Related, locus 5 (Drosophila), CHNG5, CSX, CSX1, NKX2.5, NKX2E, NKX4-1) (APC)

Ask
View Details