Anti-BBS9 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Bardet–Biedl syndrome 9 is a protein that in humans is encoded by the BBS9 gene. This gene is downregulated by parathyroid hormone in osteoblastic cells, and therefore is thought to be involved in parathyroid hormone action in bones. The exact function of this gene has not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms
Troponin I, fast skeletal muscle; Troponin I, fast-twitch isoform; TNNI2
Gene Name
BBS9
Gene ID
27241
UniProt
Q3SYG4
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human BBS9 recombinant protein (Position: Q37-L793) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .
Applications
Flow Cytometry
Field of Research
Interleukins
Purification
Immunogen affinity purified.
Form
Liquid
Function
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
References & Citations
1. Abu-Safieh, L., Al-Anazi, S., Al-Abdi, L., Hashem, M., Alkuraya, H., Alamr, M., Sirelkhatim, M. O., Al-Hassnan, Z., Alkuraya, B., Mohamed, J. Y., Al-Salem, A., Alrashed, M., and 11 others. In search of triallelism in Bardet-Biedl syndrome. Europ. J. Hum. Genet. 20: 420-427, 2012. 2. Nishimura, D. Y., Swiderski, R. E., Searby, C. C., Berg, E. M., Ferguson, A. L., Hennekam, R., Merin, S., Weleber, R. G., Biesecker, L. G., Stone, E. M., Sheffield, V. C. Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene. Am. J. Hum. Genet. 77: 1021-1033, 2005.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
108320 MW
Applications Notes
6
Gene Name Synonym
Troponin I2, fast skeletal type
Subcellular Location
Troponin complex. Cytosol. Nucleus.
Protein Name
Gamma-aminobutyric acid type B receptor subunit 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Zebrafish Delta C Antibody (zdc2) [mFluor Violet 610 SE]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP2-50371MFV610 0.1 mL
Mouse Monoclonal Zebrafish Delta C Antibody (zdc2) [mFluor Violet 610 SE]
Ask
View Details