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Anti-ARHGAP45 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity. Located in membrane.

Synonyms

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

Gene Name

ARHGAP45

Gene ID

23526

UniProt

Q92619

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human ARHGAP45 recombinant protein (Position: D111-E349) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

Flow Cytometry

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Form

Liquid

Function

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

References & Citations

1. Kreuk B , Schaefer A , Anthony E C , et al. The Human Minor Histocompatibility Antigen1 Is a RhoGAP[J]. PLoS ONE, 2013. 2. He L , Valignat M P , Zhang L , et al. ARHGAP45 controls na € ve T-and B-cell entry into lymph nodes and T-cell progenitor thymus seeding[J]. EMBO Reports, 2021.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

14377 MW

Applications Notes

6

Gene Name Synonym

Retrotransposon Gag like 10

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Lymphocyte antigen 6A-2/6E-1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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