Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Neurotensin Receptor 1/NTSR1 Antibody Picoband® Fluoro647 Conjugated

Selected Variant

A04610-4-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

Neurotensin receptor type 1 is a protein that in humans is encoded by the NTSR1 gene. Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion.

Synonyms

Thioredoxin, mitochondrial; MTRX; Mt-Trx; Thioredoxin-2; TXN2; TRX2

Gene Name

NTSR1

Gene ID

4923

UniProt

P30989

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Neurotensin Receptor 1/NTSR1 recombinant protein (Position: A15-D400) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed in adult (at protein level) and fetal tissues.

Applications

Flow Cytometry

Field of Research

Hematopoietic Progenitors, Immunology, Innate Immunity, Stem Cells, Surface Molecules

Purification

Immunogen affinity purified.

Form

Liquid

Function

Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.

References & Citations

1. Huang, W., Masureel, M., Qu, Q., Janetzko, J., Inoue, A., Kato, H. E., Robertson, M. J., Nguyen, K. C., Glenn, J. S., Skiniotis, G., Kobilka, B. K. Structure of the neurotensin receptor 1 in complex with beta-arrestin 1. Nature 579: 303-308, 2020. 2. Kato, H. E., Zhang, Y., Hu, H., Suomivuori, C.-M., Kadji, F. M. N., Aoki, J., Krishna Kumar, K., Fonseca, R., Hilger, D., Huang, W., Latorraca, N. R., Inoue, A., Dror, R. O., Kobilka, B. K., Skiniotis, G. Conformational transitions of a neurotensin receptor 1-G (i1) complex. Nature 572: 80-85, 2019. 3. Laurent, P., Clerc, P., Mattei, M.-G., Forgez, P., Dumont, X., Ferrara, P., Caput, D., Rostene, W. Chromosomal localization of mouse and human neurotensin receptor genes. Mammalian Genome 5: 303-306, 1994.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Thioredoxin 2

Subcellular Location

Mitochondrion.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD45 / LCA (136-4B5), CF740 conjugate, 0.1mg/mL
BNC740173-100 1x 100 µL

CD45 / LCA (136-4B5), CF740 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Anti-CD43/SPN Antibody Picoband® (monoclonal, 4I3)
M01296-1 100 µg/Vial

Anti-CD43/SPN Antibody Picoband® (monoclonal, 4I3)

Sign In for Pricing
View Details
Anti-Poliovirus Receptor/PVR Antibody Picoband®
A00664-4 100 µg/Vial

Anti-Poliovirus Receptor/PVR Antibody Picoband®

Sign In for Pricing
View Details
Anti-TNF alpha Antibody Picoband®, iFluor647 Conjugate
PA1079-iFluor647 100 µg

Anti-TNF alpha Antibody Picoband®, iFluor647 Conjugate

Sign In for Pricing
View Details
Anti-BRD4 Antibody Picoband®, HRP Conjugate
A00123-3-HRP 100 µg/Vial

Anti-BRD4 Antibody Picoband®, HRP Conjugate

Sign In for Pricing
View Details
Cytokeratin, multi (KRT/457), Biotin conjugate, 0.1mg/mL