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Anti-CENPI Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Centromere protein I is a protein that in humans is encoded by the CENPI gene.

Synonyms

Pre T-cell antigen receptor alpha; pT-alpha; pTa; pT-alpha-TCR; PTCRA

Gene Name

CENPI

Gene ID

2491

UniProt

Q92674

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human CENPI recombinant protein (Position: K120-C604) .

Clonality

Polyclonal

Tissue Specificity

Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Applications

Flow Cytometry

Field of Research

Hematopoietic Progenitors, Lymphoid, Stem Cells, T Lymphocytic Lineage

Purification

Immunogen affinity purified.

Form

Liquid

Function

The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. .

References & Citations

1. Liu, S.-T., Hittle, J. C., Jablonski, S. A., Campbell, M. S., Yoda, K., Yen, T. J. Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. Nature Cell Biol. 4: 341-345, 2003. 2. Roberts, R. G., Kendall, E., Vetrie, D., Bobrow, M. Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene. Genomics 37: 122-124, 1996. 3. Slegtenhorst-Eegdeman, K. E., Post, M., Baarends, W. M., Themmen, A. P. N., Grootegoed, J. A. Regulation of gene expression in Sertoli cells by follicle-stimulating hormone (FSH) : cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein. Molec. Cell. Endocr. 108: 115-124, 1995.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

41409 MW

Applications Notes

6

Gene Name Synonym

Pre T cell antigen receptor alpha

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Protein NDRG3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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