Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-PC4/SUB1 Antibody Picoband® (monoclonal, 2D13E3) Fluoro594 Conjugated

Product Specifications

Background

Activated RNA polymerase II transcriptional coactivator p15, also known as positive cofactor 4 (PC4) or SUB1 homolog, is a protein that in humans is encoded by the SUB1 gene. This gene is mapped to 5p13.3. The transcriptional cofactor PC4 is an ancient single-strand DNA (ssDNA) -binding protein that has a homologue in bacteriophage T5 where it is likely the elusive replicative ssDNA-binding protein. The recombinant PC4 is shown to function identically to the native protein through its interaction with TAFs.

Synonyms

Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein; ACTN3

Gene Name

SUB1

Gene ID

10923

UniProt

P53999

Host

Mouse

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PC4/SUB1 recombinant protein (Position: N62-L127) .

Clonality

Monoclonal

Clone

Clone: 2D13E3

Tissue Specificity

Expressed only in a subset of type 2 skeletal muscle fibers.

Applications

Flow Cytometry

Field of Research

Actin Binding Proteins, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

References & Citations

1. Entrez Gene SUB1: SUB1 homolog (S. cerevisiae) . 2. Kretzschmar M, Kaiser K, Lottspeich F, Meisterernst M (August 1994) . A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators. Cell 78 (3) : 525–34. 3. Ge H, Roeder RG (August 1994) . Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell 78 (3) : 513–23.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Actinin alpha 3 (gene/pseudogene)

Isotype

Mouse IgG2b

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse Hs6st3 Pre-designed siRNA Set B
SI106372B 1 Each

Mouse Hs6st3 Pre-designed siRNA Set B

Sign In for Pricing
View Details
Anti-Phospho-Hrs (Y216) antibody
STJ90292 200 µl

Anti-Phospho-Hrs (Y216) antibody

Sign In for Pricing
View Details
Fgf20 sgRNA CRISPR Lentivector (Rat) (Target 2)
K6976903 1.0 µg DNA

Fgf20 sgRNA CRISPR Lentivector (Rat) (Target 2)

Sign In for Pricing
View Details
VTN ORF Vector (Human) (pORF)
50226011 1.0 µg DNA

VTN ORF Vector (Human) (pORF)

Sign In for Pricing
View Details
RCAN1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K1802606 1.0 µg DNA

RCAN1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

Sign In for Pricing
View Details
ACTL10 Human shRNA Plasmid Kit (Locus ID 170487)
TL314331 1 Kit

ACTL10 Human shRNA Plasmid Kit (Locus ID 170487)

Sign In for Pricing
View Details