Anti-SP6 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
SP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif) . These transcription factors bind to GC-rich sequences and related GT and CACCC boxes.
Synonyms
Transcription factor Sp6; Krueppel-like factor 14; SP6; KLF14
Gene Name
SP6
Gene ID
80320
UniProt
Q3SY56
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human SP6 recombinant protein (Position: H18-N376) .
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
Flow Cytometry
Field of Research
Cancer, Cell Biology, Cell Cycle, Cell Division, Cell Type Marker, Cell Type Markers, Neurogenesis, Neurology Process, Neuron Marker, Neuroscience, Tags & Cell Markers, Tumor Biomarkers
Purification
Immunogen affinity purified.
Form
Liquid
Function
Promotes cell proliferation.
References & Citations
1. Gross, M. B. Personal Communication. Baltimore, Md. 12/18/2014. 2. Nakamura, T., de Vega, S., Fukumoto, S., Jimenez, L., Unda, F., Yamada, Y. Transcription factor epiprofin is essential for tooth morphogenesis by regulating epithelial cell fate and tooth number. J. Biol. Chem. 283: 4825-4833, 2008. 3. Nakamura, T., Unda, F., de-Vega, S., Vilaxa, A., Fukumoto, S., Yamada, K. M., Yamada, Y. The Kruppel-like factor epiprofin is expressed by epithelium of developing teeth, hair follicles, and limb buds and promotes cell proliferation. J. Biol. Chem. 279: 626-634, 2004.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Sp6 transcription factor
Subcellular Location
Nucleus.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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