Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Cdk2 Antibody Picoband® (monoclonal, 6D5B5)

Boster Bio Anti-Cdk2 Antibody Picoband® (monoclonal, 6D5B5) catalog # M00166-4. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

CDK2, Cyclin-Dependent Kinase2, is also known as P33. The CDK2 protein was highly homologous to p34 (CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34 (cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34 (cdc2) /cyclin A. The gene for p33 shares 65% sequence identity with p34 (cdc2) . P33 (cdk2) plays a unique role in cell cycle regulation of vertebrate cells.

Synonyms

Solute carrier family 2, facilitated glucose transporter member 1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter; SLC2A1; GLUT1

Gene Name

CDK2

Gene ID

1017

UniProt

P24941

Host

Mouse

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Cdk2 recombinant protein (Position: E81-L298) . Human Cdk2 shares 98.6% amino acid (aa) sequence identity with rat Cdk2.

Clonality

Monoclonal

Clone

Clone: 6D5B5

Tissue Specificity

Detected in erythrocytes (at protein level) . Expressed at variable levels in many human tissues.

Applications

IHC, WB

Field of Research

Channels, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.

References & Citations

1. Demetrick, D. J., Zhang, H., Beach, D. H.Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes.Cytogenet. Cell Genet. 66: 72-74, 1994. 2. Tsai, L.-H., Harlow, E., Meyerson, M.Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated P33 kinase.Nature 353: 174-177, 1991.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

46659 MW

Observed Molecular Weight

30 kDa

Gene Name Synonym

Solute carrier family 2 (facilitated glucose transporter), member 1

Subcellular Location

Cell membrane. Multi-pass membrane protein. Melanosome.

Protein Name

Isocitrate dehydrogenase [NADP] cytoplasmic

Isotype

Mouse IgG2b

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

PNOC Antibody
A47104-100UL 100 µL

PNOC Antibody

Ask
View Details
Rat anti-CD16/CD32 Antibody
MBS4513958-01 0.05 mL

Rat anti-CD16/CD32 Antibody

Ask
View Details
Rat anti-CD16/CD32 Antibody
MBS4513958-02 0.1 mL

Rat anti-CD16/CD32 Antibody

Ask
View Details
Rat anti-CD16/CD32 Antibody
MBS4513958-03 5x 0.1 mL

Rat anti-CD16/CD32 Antibody

Ask
View Details
PE anti-human CD213a2 (IL13Rα2)
GT14216 100 Tests

PE anti-human CD213a2 (IL13Rα2)

Ask
View Details
Dextrose Broth (Powder)
D3222-05 500 g

Dextrose Broth (Powder)

Ask
View Details