Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MLX Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Max-like protein X is a protein that in humans is encoded by the MLX gene. The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Synonyms

Aquaporin-5; AQP-5; AQP5

Gene Name

MLX

Gene ID

6945

UniProt

Q9UH92

Host

Rabbit

Reactivity

Human, Monkey, Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human MLX, which shares 97.3% amino acid (aa) sequence identity with mouse MLX.

Clonality

Polyclonal

Tissue Specificity

Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.

Applications

Flow Cytometry

Field of Research

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Required for TRPV4 activation by hypotonicity (PubMed:16571723) . Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (PubMed:16571723) .

References & Citations

1. Billin, A. N., Eilers, A. L., Coulter, K. L., Logan, J. S., Ayer, D. E. MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a Max-like network. Molec. Cell. Biol. 20: 8845-8854, 2000. 2. Billin, A. N., Eilers, A. L., Queva, C., Ayer, D. E. Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors. J. Biol. Chem. 274: 36344-36350, 1999. 3. Bjerknes, M., Cheng, H. TCFL4: a gene at 17q21.1 encoding a putative basic helix-loop-helix leucine-zipper transcription factor. Gene 181: 7-11, 1996.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64406 MW

Applications Notes

6

Gene Name Synonym

Aquaporin 5

Subcellular Location

Apical cell membrane.

Protein Name

Transcription factor E2F3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Menadione Sodium Bisulphite 95.0% (Vitamin K3; W.S.) Cell Culture Tested
TC1151-01 25 g

Menadione Sodium Bisulphite 95.0% (Vitamin K3; W.S.) Cell Culture Tested

Ask
View Details
Menadione Sodium Bisulphite 95.0% (Vitamin K3; W.S.) Cell Culture Tested
TC1151-02 100 g

Menadione Sodium Bisulphite 95.0% (Vitamin K3; W.S.) Cell Culture Tested

Ask
View Details
Bicalutamide 100mg
A10142-100 100 mg

Bicalutamide 100mg

Ask
View Details
Human RIF1 activation kit by CRISPRa
GA110584 1 Kit

Human RIF1 activation kit by CRISPRa

Ask
View Details
Phosphoinositide-3-Kinase Catalytic Beta Polypeptide (Biotin)
549262 200 µL

Phosphoinositide-3-Kinase Catalytic Beta Polypeptide (Biotin)

Ask
View Details
Tetrapeptide-1
BA5549-10 10 mg

Tetrapeptide-1

Ask
View Details