Anti-L1RE1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome. May function as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.

Synonyms

Follicular dendritic cell secreted peptide; FDC secreted protein; FDC-SP; FDCSP; C4orf7; UNQ733/PRO1419

Gene Name

L1RE1

Gene ID

4029

UniProt

Q9UN81

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human L1RE1 recombinant protein (Position: Q147-E324) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

Flow Cytometry

Field of Research

Immunology, Secreted Molecules

Purification

Immunogen affinity purified.

Form

Liquid

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Baillie, J. K., Barnett, M. W., Upton, K. R., Gerhardt, D. J., Richmond, T. A., De Sapio, F., Brennan, P., Rizzu, P., Smith, S., Fell, M., Talbot, R. T., Gustincich, S., Freeman, T. C., Mattick, J. S., Hume, D. A., Heutink, P., Carninci, P., Jeddeloh, J. A., Faulkner, G. J. Somatic retrotransposition alters the genetic landscape of the human brain. Nature 479: 534-537, 2011. 2. Boeke, J. D. LINEs and Alus--the polyA connection. Nature Genet. 16: 6-7, 1997. 3. Brosius, J., Gould, S. J. On 'genomenclature': a comprehensive (and respectful) taxonomy for pseudogenes and other 'junk DNA.' Proc. Nat. Acad. Sci. 89: 10706-10710, 1992.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

9700 MW

Applications Notes

Gene Name Synonym

Follicular dendritic cell secreted peptide

Subcellular Location

Secreted.

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-L1RE1 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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