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Anti-RPL32 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

60S ribosomal protein L32 is a protein that in humans is encoded by the RPL32 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family of ribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it is believed to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Synonyms

Max dimerization protein 1; Max dimerizer 1; Protein MAD; MXD1; MAD

Gene Name

RPL32

Gene ID

6161

UniProt

P62910

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RPL32 recombinant protein (Position: R48-L129) .

Clonality

Polyclonal

Applications

Flow Cytometry

Field of Research

Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Transcription

Purification

Immunogen affinity purified.

Form

Liquid

Function

Transcriptional repressor. MAD binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MAD thus antagonizes MYC transcriptional activity by competing for MAX.

References & Citations

1. Neto, E. D. , Correa, R. G. , & Verjovski-Almeida, S. . (2000) . Shotgun sequencing of the human transcriptome with orf expressed sequence tags. Proceedings of the National Academy of Sciences, 97 (7), 3491-3496.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

MAX dimerization protein 1

Subcellular Location

Nucleus.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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