Anti-CITED1 Antibody Picoband® Fluoro647 Conjugated
Product Specifications
Background
Cbp/p300-interacting transactivator 1 is a protein that in humans is encoded by the CITED1 gene. This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described.
Synonyms
Vasoactive intestinal polypeptide receptor 1; VIP-R-1; Pituitary adenylate cyclase-activating polypeptide type II receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; VPAC1; VIPR1
Gene Name
CITED1
Gene ID
4435
UniProt
Q99966
Host
Rabbit
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human CITED1 recombinant protein (Position: M1-A130) .
Clonality
Polyclonal
Tissue Specificity
In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T- cell lines Peer, MOLT-4, HSB and YT.
Applications
Flow Cytometry
Field of Research
Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells
Purification
Immunogen affinity purified.
Form
Liquid
Function
PACAP-27 > PACAP-38.
References & Citations
1. Fenner, M. H., Parrish, J. E., Boyd, Y., Reed, V., MacDonald, M., Nelson, D. L., Isselbacher, K. J., Shioda, T. MSG1 (melanocyte-specific gene 1) : mapping to chromosome Xq13.1, genomic organization, and promoter analysis. Genomics 51: 401-407, 1998. 2. Shioda, T., Fenner, M. H., Isselbacher, K. J. Msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc. Nat. Acad. Sci. 93: 12298-12303, 1996. 3. Shioda, T., Fenner, M. H., Isselbacher, K. J. MSG1 and its related protein MRG1 share a transcription activating domain. Gene 204: 235-241, 1997.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Vasoactive intestinal peptide receptor 1
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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