Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MTHFD1L Antibody Picoband®

Boster Bio Anti-MTHFD1L Antibody Picoband® catalog # A06289-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Monofunctional C1-tetrahydrofolate synthase, mitochondrial also known as formyltetrahydrofolate synthetase, is an enzyme that in humans is encoded by the MTHFD1L gene (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like) . The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1; ELAVL2; HUB

Gene Name

MTHFD1L

Gene ID

25902

UniProt

Q6UB35

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MTHFD1L recombinant protein (Position: R43-V833) .

Clonality

Polyclonal

Tissue Specificity

Brain; neural-specific.

Applications

ELISA, Flow Cytometry, IF, IHC, ICC, WB

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.

References & Citations

1. Christensen, K. E., Patel, H., Kuzmanov, U., Mejia, N. R., MacKenzie, R. E. Disruption of the Mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria. J. Biol. Chem. 280: 7597-7602, 2005. 2. Momb, J., Lewandowski, J. P., Bryant, J. D., Fitch, R., Surman, D. R., Vokes, S. A., Appling, D. R. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice. Proc. Nat. Acad. Sci. 110: 549-554, 2013. 3. Prasannan, P., Pike, S., Peng, K., Shane, B., Appling, D. R. Human mitochondrial C (1) -tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary cells. J. Biol. Chem. 278: 43178-43187, 2003.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

49655 MW

Observed Molecular Weight

106 kDa

Applications Notes

6

Gene Name Synonym

ELAV like RNA binding protein 2

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm.

Protein Name

AP-2 complex subunit mu

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant Oryza sativa Cytochrome b6-f complex subunit 5 (petG), partial
MBS1188164-01 1 mg (E-Coli)

Recombinant Oryza sativa Cytochrome b6-f complex subunit 5 (petG), partial

Ask
View Details
Recombinant Oryza sativa Cytochrome b6-f complex subunit 5 (petG), partial
MBS1188164-02 1 mg (Yeast)

Recombinant Oryza sativa Cytochrome b6-f complex subunit 5 (petG), partial

Ask
View Details
Centrin 3 (CETN3) Mouse Monoclonal Antibody [Clone ID: OTI1E3]
TA805871 100 µL

Centrin 3 (CETN3) Mouse Monoclonal Antibody [Clone ID: OTI1E3]

Ask
View Details
Tmem28 AAV Vector (Mouse) (CMV)
47035104 1 µg

Tmem28 AAV Vector (Mouse) (CMV)

Ask
View Details
Porcine Ovarian Endometrial Primary Cells
CC7F869 5x 10^5 Cells/Vial

Porcine Ovarian Endometrial Primary Cells

Ask
View Details
Recombinant Human ZBTB12 Protein (C-His)
32-10540-50 50 µg

Recombinant Human ZBTB12 Protein (C-His)

Ask
View Details