Anti-HBD Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Hemoglobin subunit delta is a protein that in humans is encoded by the HBD gene. The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'.
Synonyms
Hemoglobin subunit delta; Delta-globin; Hemoglobin delta chain; HBD
Gene Name
HBD
Gene ID
3045
UniProt
P02042
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human HBD recombinant protein (Position: M1-H147) .
Clonality
Polyclonal
Tissue Specificity
Red blood cells.
Applications
Flow Cytometry
Field of Research
Biochemicals, Chemical Type, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction
Purification
Immunogen affinity purified.
Form
Liquid
Function
Involved in oxygen transport from the lung to the various peripheral tissues.
References & Citations
1. Giardina B, Messana I, Scatena R, Castagnola M (1995) . The multiple functions of hemoglobin.. Crit. Rev. Biochem. Mol. Biol. 30 (3) : 165–96. 2. Higgs DR, Vickers MA, Wilkie AO, Pretorius IM, Jarman AP, Weatherall DJ (May 1989) . A review of the molecular genetics of the human alpha-globin gene cluster. Blood. 73 (5) : 1081–104.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Hemoglobin subunit delta
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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