Anti-Aldolase C/ALDOC Antibody Picoband® Fluoro647 Conjugated

Aldolase C, fructose-bisphosphate (ALDOC, or ALDC), is an enzyme that, in humans, is encoded by the ALDOC gene on chromosome 17. This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.

A synthetic peptide corresponding to a sequence at the N-terminus of human Aldolase C/ALDOC, which shares 100% and 93.8% amino acid (aa) sequence identity with mouse and rat ALDOC, respectively.

Cell Biology, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Interferons, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes

1. Buono, P., Paolella, G., Mancini, F. P., Izzo, P., Salvatore, F. The complete nucleotide sequence of the gene coding for the human aldolase C. Nucleic Acids Res. 16: 4733 only, 1988. 2. Rocchi, M., Vitale, E., Covone, A., Romeo, G., Santamaria, R., Buono, P., Paolella, G., Salvatore, F. Assignment of human aldolase C gene to chromosome 17, region cen--q21.1. Hum. Genet. 82: 279-282, 1989. 3. Rottmann, W. H., Deselms, K. R., Niclas, J., Camerato, T., Holman, P. S., Green, C. J., Tolan, D. R. The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones. Biochimie 69: 137-145, 1987.