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Anti-TUBGCP3 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Gamma-tubulin complex component 3 is a protein that in humans is encoded by the TUBGCP3 gene. TUBGCP3, also named as γ‐tubulin complex protein 3, localized to the centrosome, is a member of γ-tubulin complex proteins which play key roles in microtubule nucleation and organization. It has been reported that TUBGCP3 rotation can bring γ-tubulin molecules into proximity. 15719-1-AP antibody detects the isoform proteins around 95-101 kDa and 50 kDa in SDS-PAGE.

Synonyms

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

Gene Name

TUBGCP3

Gene ID

10426

UniProt

Q96CW5

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TUBGCP3 recombinant protein (Position: M1-R802) .

Clonality

Polyclonal

Tissue Specificity

Brain. Expression restricted to astrocytes.

Applications

Flow Cytometry

Field of Research

Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 12/18/2017. 2. Murphy, S. M., Urbani, L., Stearns, T. The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components Spc97p and Spc98p. J. Cell Biol. 141: 663-674, 1998. 3. Riehlman, T. D., Olmsted, Z. T., Branca, C. N., Winnie, A. M., Seo, L., Cruz, L. O., Paluh, J. L. Functional replacement of fission yeast gamma-tubulin small complex proteins Alp4 and Alp6 by human GCP2 and GCP3. J. Cell Sci. 126: 4406-4413, 2013.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

29370 MW

Applications Notes

6

Gene Name Synonym

NOVA alternative splicing regulator 2

Subcellular Location

Nucleus.

Protein Name

Aquaporin-6

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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