Anti-Nucleostemin/GNL3 Antibody Picoband® Fluoro488 Conjugated
Product Specifications
Background
Guanine nucleotide-binding protein-like 3, also known as nucleostemin, is a protein that in humans is encoded by the GNL3 gene. The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms
CD48 antigen; B-lymphocyte activation marker BLAST-1; BCM1 surface antigen; Leukocyte antigen MEM-102; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; TCT.1; CD48; CD48; BCM1, BLAST1
Gene Name
GNL3
Gene ID
26354
UniProt
Q9BVP2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human Nucleostemin/GNL3 recombinant protein (Position: R45-V549) .
Clonality
Polyclonal
Applications
Flow Cytometry
Field of Research
Cell Type Markers, Immunology
Purification
Immunogen affinity purified.
Form
Liquid
Function
Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
References & Citations
1. Charpentier, A. H., Bednarek, A. K., Daniel, R. L., Hawkins, K. A., Laflin, K. J., Gaddis, S., MacLeod, M. C., Aldaz, C. M. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res. 60: 5977-5983, 2000. 2. Dai, M.-S., Sun, X.-X., Lu, H. Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2. Molec. Cell. Biol. 28: 4365-4376, 2008. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 6/29/2012.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
27683 MW
Applications Notes
6
Gene Name Synonym
CD48 antigen
Subcellular Location
Cell membrane ; Lipid-anchor, GPI-anchor .
Protein Name
CD48 antigen
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1475342-01 0.02 mg (E-Coli)
Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)
Sign In for Pricing
View Details 
MBS1475342-02 0.1 mg (E-Coli)
Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)
Sign In for Pricing
View Details 
MBS1475342-03 0.02 mg (Yeast)
Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)
Sign In for Pricing
View Details 
MBS1475342-04 0.1 mg (Yeast)
Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)
Sign In for Pricing
View Details MBS1475342-05 0.02 mg (Baculovirus)
Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)
Sign In for Pricing
View Details MBS1475342-06 0.02 mg (Mammalian-Cell)
Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)
Sign In for Pricing
View Details