Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-BZW2 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Basic Leucine Zipper and W2 Domain-Containing Protein 2 is a protein that is encoded by the BZW2 gene. BZW2, also known as HSPC028 or MSTP017, is a 419 amino acid protein that contains one W2 domain and is thought to be involved in neuronal differentiation. The gene encoding BZW2 maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia.

Synonyms

Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166; EVA1A; FAM176A; TMEM166; SP24

Gene Name

BZW2

Gene ID

28969

UniProt

Q9Y6E2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human BZW2 recombinant protein (Position: E21-A292) .

Clonality

Polyclonal

Tissue Specificity

Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Applications

Flow Cytometry

Field of Research

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes

Purification

Immunogen affinity purified.

Form

Liquid

Function

Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.

References & Citations

1. Gao, H., Yu, G., Zhang, X., Yu, S., Sun, Y., Li, Y. BZW2 gene knockdown induces cell growth inhibition, G1 arrest and apoptosis in muscle-invasive bladder cancers: a microarray pathway analysis. J. Cell. Molec. Med. 23: 3905-3915, 2019. 2. Gross, M. B. Personal Communication. Baltimore, Md. 4/14/2021. 3. Hiraishi, H., Oatman, J., Haller, S. L., Blunk, L., McGivern, B., Morris, J., Papadopoulos, E., Gutierrez, W., Gordon, M., Bokhari, W., Ikeda, Y., Miles, D., Fellers, J., Asano, M., Wagner, G., Tazi, L., Rothenburg, S., Brown, S. J., Asano, K. Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression. Nucleic Acids Res. 42: 10321-10330, 2014.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Eva-1 homolog A, regulator of programmed cell death

Subcellular Location

Endoplasmic reticulum membrane, Single-pass membrane protein, Lysosome membrane.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CLEC4G Rabbit pAb (APR18126N)
APR18126N-01 50 µL

CLEC4G Rabbit pAb (APR18126N)

Ask
View Details
CLEC4G Rabbit pAb (APR18126N)
APR18126N-02 100 µL

CLEC4G Rabbit pAb (APR18126N)

Ask
View Details
CLEC4G Rabbit pAb (APR18126N)
APR18126N-03 200 µL

CLEC4G Rabbit pAb (APR18126N)

Ask
View Details
STING agonist-44
HY-176257 1 Each

STING agonist-44

Ask
View Details
Bovine Epithelial neutrophil activating peptide 78 ELISA Kit
OM618295 96 Strip Well

Bovine Epithelial neutrophil activating peptide 78 ELISA Kit

Ask
View Details
Lentiviral human SEC11C sgRNA gene knockout kit - Lentiviral human SEC11C sgRNA gene knockout kit (25)
GTR15392457 1 Vial

Lentiviral human SEC11C sgRNA gene knockout kit - Lentiviral human SEC11C sgRNA gene knockout kit (25)

Ask
View Details