Anti-ADORA2B Antibody Picoband® Fluoro594 Conjugated

The adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human adenosine A2b receptor gene which encodes it. This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.

1. Corset, V., Nguyen-Ba-Charvet, K. T., Forcet, C., Moyse, E., Chedotal, A., Mehlen, P. Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor. Nature 407: 747-750, 2000. 2. Kataoka, S., Baquero, A., Yang, D., Shultz, N., Vandenbeuch, A., Ravid, K., Kinnamon, S. C., Finger, T. E. A2BR adenosine receptor modulates sweet taste in circumvallate taste buds. PLoS One 7: e30032, 2012. Note: Electronic Article. 3. Libert, F., Passage, E., Parmentier, M., Simons, M.-J., Vassart, G., Mattei, M.-G. Chromosomal mapping of A1 and A2 adenosine receptors, VIP receptor, and a new subtype of serotonin receptor. Genomics 11: 225-227, 1991. Note: Erratum: Genomics 23: 305 only, 1994.