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Anti-QSOX2 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

This gene encodes a member of the sulfhydryl oxidase protein family. Members of this family catalyze formation of disulfide bonds. A similar protein in humans may sensitize neuroblastoma cells to interferon gamma-induced cell death. Alternate splicing results in multiple transcript variants.

Synonyms

Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

Gene Name

QSOX2

Gene ID

169714

UniProt

Q6ZRP7

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human QSOX2 recombinant protein (Position: R102-P523) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in brain. .

Applications

Flow Cytometry

Field of Research

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Tumor Biomarkers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

References & Citations

1. Alon, A., Grossman, I., Gat, Y., Kodali, V. K., DiMaio, F., Mehlman, T., Haran, G., Baker, D., Thorpe, C., Fass, D. The dynamic disulphide relay of quiescin sulphydryl oxidase. Nature 488: 414-418, 2012. 2. Wittke, I., Wiedemeyer, R., Pillmann, A., Savelyeva, L., Westermann, F., Schwab, M. Neuroblastoma-derived sulfhydryl oxidase, a new member of the sulfhydryl oxidase/Quiescin6 family, regulates sensitization to interferon gamma-induced cell death in human neuroblastoma cells. Cancer Res. 63: 7742-7752, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

41409 MW

Applications Notes

6

Gene Name Synonym

Protein NDRG3

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

Protein NDRG3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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