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Anti-NGDN Antibody Picoband®

Boster Bio Anti-NGDN Antibody Picoband® catalog # A10259-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Neuroguidin is an EIF4E-binding protein that interacts with CPEB and functions as a translational regulatory protein during development of the vertebrate nervous system.

Synonyms

Pre T-cell antigen receptor alpha; pT-alpha; pTa; pT-alpha-TCR; PTCRA

Gene Name

NGDN

Gene ID

25983

UniProt

Q8NEJ9

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NGDN recombinant protein (Position: E8-K191) .

Clonality

Polyclonal

Tissue Specificity

Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Applications

WB, ICC, IF, Flow Cytometry, ELISA

Field of Research

Hematopoietic Progenitors, Lymphoid, Stem Cells, T Lymphocytic Lineage

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. .

References & Citations

1. Jung, M.-Y., Lorenz, L., Richter, J. D. Translational control by neuroguidin, a eukaryotic initiation factor 4E and CPEB binding protein. Molec. Cell Biol. 26: 4277-4287, 2006.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

41409 MW

Observed Molecular Weight

36 kDa

Applications Notes

6

Gene Name Synonym

Pre T cell antigen receptor alpha

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Protein NDRG3

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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