Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-HECTD1 Antibody Picoband®

Boster Bio Anti-HECTD1 Antibody Picoband® catalog # A08428-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

HECTD1 (E3 ubiquitin-protein ligase), which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates, may be required for development of the head mesenchyme and neural tube closure.It is also involved in sporadic Parkinson's disease (PMID:16714300) .This protein is specific to HECTD1.

Synonyms

Kallistatin; Kallikrein inhibitor; Peptidase inhibitor 4; PI-4; Serpin A4; SERPINA4; KST; PI4

Gene Name

HECTD1

Gene ID

25831

UniProt

Q9ULT8

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human HECTD1 recombinant protein (Position: D39-S566) .

Clonality

Polyclonal

Tissue Specificity

Expressed by the liver and secreted in plasma.

Applications

WB, IHC, ELISA

Field of Research

Cancer, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.

References & Citations

1. Aleidi, S. M., Yang, A., Sharpe, L. J., Rao, G., Cochran, B. J., Rye, K.-A., Kockx, M., Brown, A. J., Gelissen, I. C. The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages. Biochim. Biophys. Acta Molec. Cell Biol. Lipids 1863: 359-368, 2018. 2. D'Alonzo, D., Emch, F. H., Shen, X., Bruder, E., De Geyter, C., Zhang, H. Hectd1 is essential for embryogenesis in mice. Gene Expr. Patterns 34: 119064, 2019. Note: Electronic Article. 3. Gross, M. B. Personal Communication. Baltimore, Md. 10/29/2019.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

82457 MW

Observed Molecular Weight

290 kDa

Gene Name Synonym

Serpin family A member 4

Subcellular Location

Secreted.

Protein Name

Disintegrin and metalloproteinase domain-containing protein 2

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Caprin2 Mouse shRNA Plasmid (Locus ID 232560)
TR519849 1 Kit

Caprin2 Mouse shRNA Plasmid (Locus ID 232560)

Ask
View Details
EZH1 Rabbit pAb
E45R30387N-100 100 µL

EZH1 Rabbit pAb

Ask
View Details
Carnosine (Car)
151634 200 µL

Carnosine (Car)

Ask
View Details
Recombinant Buchnera aphidicola subsp. Baizongia pistaciae DNA polymerase III subunit beta (dnaN)
MBS1402225-01 0.02 mg (E-Coli)

Recombinant Buchnera aphidicola subsp. Baizongia pistaciae DNA polymerase III subunit beta (dnaN)

Ask
View Details
Recombinant Buchnera aphidicola subsp. Baizongia pistaciae DNA polymerase III subunit beta (dnaN)
MBS1402225-02 0.02 mg (Yeast)

Recombinant Buchnera aphidicola subsp. Baizongia pistaciae DNA polymerase III subunit beta (dnaN)

Ask
View Details
Recombinant Buchnera aphidicola subsp. Baizongia pistaciae DNA polymerase III subunit beta (dnaN)
MBS1402225-03 0.1 mg (E-Coli)

Recombinant Buchnera aphidicola subsp. Baizongia pistaciae DNA polymerase III subunit beta (dnaN)

Ask
View Details