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Anti-DNAJC11 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

DnaJ homolog subfamily C member 11 is a protein that in humans is encoded by the DNAJC11 gene. DNAJC11 is a member of the J proteins also known as HSP40 family of co-chaperones. Recently DNAJC11 has been found to interact with mitofilin, a mitochondrial inner membrane protein, indicating that it may be a molecular chaperone during mitochondrial protein import and folding.

Synonyms

Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7

Gene Name

DNAJC11

Gene ID

55735

UniProt

Q9NVH1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human DNAJC11 recombinant protein (Position: N12-Q551) .

Clonality

Polyclonal

Tissue Specificity

Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Applications

Flow Cytometry

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Immunogen affinity purified.

Form

Liquid

Function

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .

References & Citations

1. Andrews, B., Carroll, J., Ding, S., Fearnley, I. M., Walker, J. E. Assembly factors for the membrane arm of human complex I. Proc. Nat. Acad. Sci. 110: 18934-18939, 2013. 2. Katoh, M., Katoh, M. Identification and characterization of FLJ10737 and CAMTA1 genes on the commonly deleted region of neuroblastoma at human chromosome 1p36.31-p36.23. Int. J. Oncol. 23: 1219-1224, 2003.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

6

Gene Name Synonym

Interleukin 17B

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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