What sizes are available for Anti-LSM8 Antibody Picoband® (monoclonal, 6B11) Fluoro647 Conjugated?

Anti-LSM8 Antibody Picoband® (monoclonal, 6B11) Fluoro647 Conjugated is available in the following size(s): 100 µg/Vial.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

Anti-LSM8 Antibody Picoband® (monoclonal, 6B11) Fluoro647 Conjugated

Q: What is the catalog number for Anti-LSM8 Antibody Picoband® (monoclonal, 6B11) Fluoro647 Conjugated?

The catalog number for Anti-LSM8 Antibody Picoband® (monoclonal, 6B11) Fluoro647 Conjugated is M10947-Fluoro647.

Product Specifications

Background

U6 snRNA-associated Sm-like protein LSm8 is a protein that in humans is encoded by the LSM8 gene. This gene encodes a member of the like-Sm family of proteins. The encoded protein consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.

Synonyms

Gene Name

LSM8

Gene ID

51691

UniProt

O95777

Host

Mouse

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human LSM8 recombinant protein (Position: M1-H96) .

Clonality

Monoclonal

Clone

Clone: 6B11

Tissue Specificity

Ubiquitously expressed with highest levels in spleen, thymus and immature brain.

Applications

Flow Cytometry

Field of Research

Chaperones, Protein Trafficking, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Mitochondrial membrane ATP synthase (F (1) F (0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F (1) - containing the extramembraneous catalytic core, and F (0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F (1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F (0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha (3) beta (3) subcomplex and subunit a/ATP6 static relative to the rotary elements.

References & Citations

1. Achsel, T., Brahms, H., Kastner, B., Bachi, A., Wilm, M., Luhrmann, R. A doughnut-shaped heteromer of human Sm-like proteins binds to the 3-prime end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO J. 18: 5789-5802, 1999. 2. Salgado-Garrido, J., Bragado-Nilsson, E., Kandels-Lewis, S., Seraphin, B. Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin. EMBO J. 18: 3451-3462, 1999.