Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-EIF5 Antibody Picoband®

Boster Bio Anti-EIF5 Antibody Picoband® catalog # A04623-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene. Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations.

Synonyms

Type I iodothyronine deiodinase; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinase; DIO1; ITDI1; TXDI1

Gene Name

EIF5

Gene ID

1983

UniProt

P55010

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human EIF5 recombinant protein (Position: D11-D423) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed in adult (at protein level) and fetal tissues.

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Cancer, Oncoproteins/Suppressors, Tumor Suppressors

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine) . Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.

References & Citations

1. Das, S., Ghosh, R., Maitra, U. Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein. J. Biol. Chem. 276: 6720-6726, 2001. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 5/5/2010. 3. Jennings, M. D., Pavitt, G. D. eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation. Nature 465: 378-381, 2010. Note: Erratum: Nature 468: 122 only, 2010.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

49 kDa

Applications Notes

6

Gene Name Synonym

Iodothyronine deiodinase 1

Subcellular Location

Endoplasmic reticulum membrane. Single-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Magic™ Membrane Protein Human OR4X2 (Olfactory receptor family 4 subfamily X member 2) Full Length
MPC2388K Each

Magic™ Membrane Protein Human OR4X2 (Olfactory receptor family 4 subfamily X member 2) Full Length

Sign In for Pricing
View Details
Alexa Fluor® 488 anti-HDAC1 Phospho (Ser406)
GT18786 25 Tests

Alexa Fluor® 488 anti-HDAC1 Phospho (Ser406)

Sign In for Pricing
View Details
SH2D7 Rabbit Polyclonal Antibody (BF594)
orb2441676 100 µL

SH2D7 Rabbit Polyclonal Antibody (BF594)

Sign In for Pricing
View Details
Cluster of Differentiation 320 (CD320) Antibody
abx027232-01 80 µL

Cluster of Differentiation 320 (CD320) Antibody

Sign In for Pricing
View Details
Cluster of Differentiation 320 (CD320) Antibody
abx027232-02 400 µL

Cluster of Differentiation 320 (CD320) Antibody

Sign In for Pricing
View Details
WDR62 3'UTR Luciferase Stable Cell Line
TU028435 1.0 mL

WDR62 3'UTR Luciferase Stable Cell Line

Sign In for Pricing
View Details