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Anti-GOLPH2/GOLM1 Antibody Picoband® Fluoro647 Conjugated

Product Specifications

Background

Golgi membrane protein 1 (GOLM1) also known as Golgi phosphoprotein 2 or Golgi membrane protein GP73 is a protein that in humans is encoded by the GOLM1 gene. The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene.

Synonyms

Cerebellar degeneration-related protein 2; Major Yo paraneoplastic antigen; Paraneoplastic cerebellar degeneration-associated antigen; CDR2; PCD17

Gene Name

GOLM1

Gene ID

51280

UniProt

Q8NBJ4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human GOLM1 recombinant protein (Position: S37-L401) .

Clonality

Polyclonal

Tissue Specificity

Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

Applications

Flow Cytometry

Field of Research

Autoimmune, Cancer, Immune System Diseases, Immunology, Oncoproteins, Tumor Biomarkers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) . .

References & Citations

1. Kladney, R. D., Bulla, G. A., Guo, L., Mason, A. L., Tollefson, A. E., Simon, D. J., Koutoubi, Z., Fimmel, C. J. GP73, a novel Golgi-localized protein upregulated by viral infection. Gene 249: 53-65, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

51855 MW

Applications Notes

6

Gene Name Synonym

Cerebellar degeneration related protein 2

Subcellular Location

Cytoplasm.

Protein Name

Cerebellar degeneration-related protein 2

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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