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Anti-SLC44A2 Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Choline transporter-like protein 2 is a protein that in humans is encoded by the SLC44A2 gene. CTL2 is a multi-pass membrane protein expressed in cells of the inner ear. CTL2 is a possible candidate for autoimmune hearing loss in humans. Present in supporting cells of the inner ear (at protein level) . Only isoform 3 is expressed in inner ear vestibular tissue.

Synonyms

Prion-like protein doppel; PrPLP; Prion protein 2; PRND; DPL; UNQ1830/PRO3443

Gene Name

Slc44a2

Gene ID

68682

UniProt

Q8BY89

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse SLC44A2 recombinant protein (Position: M1-S706) .

Clonality

Polyclonal

Tissue Specificity

Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level) .

Applications

Flow Cytometry

Field of Research

Neurodegenerative Disease, Neurology Process, Neuroscience

Purification

Immunogen affinity purified.

Form

Liquid

Function

Required for normal acrosome reaction and for normal male fertility (By similarity) . Can bind Cu (2+) (PubMed:15218028, PubMed:20411530) .

References & Citations

1. Greinacher, A., Wesche, J., Hammer, E., Furll, B., Volker, U., Reil, A., Bux, J. Characterization of the human neutrophil alloantigen-3a. Nature Med. 16: 45-48, 2010. 2. O'Regan, S., Traiffort, E., Ruat, M., Cha, N., Compaore, D., Meunier, F.-M. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins. Proc. Nat. Acad. Sci. 97: 1835-1840, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

39411 MW

Applications Notes

6

Gene Name Synonym

Prion like protein doppel

Subcellular Location

Cell membrane.

Protein Name

Zinc finger protein Helios

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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