Anti-PFAS Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis.
Synonyms
S-arrestin; 48 kDa protein; Retinal S-antigen; S-AG; Rod photoreceptor arrestin; SAG
Gene Name
PFAS
Gene ID
5198
UniProt
O15067
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human PFAS recombinant protein (Position: R330-S569) .
Clonality
Polyclonal
Tissue Specificity
Retina and pineal gland.
Applications
Flow Cytometry
Field of Research
DNA/RNA, Epigenetics and Nuclear Signaling, Nucleus, RNA Processing, Subcellular Markers, Tags & Cell Markers
Purification
Immunogen affinity purified.
Form
Liquid
Function
Arrestin is one of the major proteins of the ros (retinal rod outer segments) ; it binds to photoactivated- phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
References & Citations
1. Barnes, T. S., Bleskan, J. H., Hart, I. M., Walton, K. A., Barton, J. W., Patterson, D. Purification of, generation of monoclonal antibodies to, and mapping of phosphoribosyl N-formylglycinamide amidotransferase. Biochemistry 33: 1850-1860, 1994. 2. Brodsky, G., Barnes, T., Bleskan, J., Becker, L., Cox, M., Patterson, D. The human GARS-AIRS-GART gene encodes two proteins which are differentially expressed during human brain development and temporally overexpressed in cerebellum of individuals with Down syndrome. Hum. Molec. Genet. 6: 2043-2050, 1997.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
64133 MW
Applications Notes
6
Gene Name Synonym
S-antigen visual arrestin
Subcellular Location
Nucleus, nucleoplasm . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. These granules are not identical with P bodies or stress granules. .
Protein Name
Heterogeneous nuclear ribonucleoprotein L
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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