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Anti-ARID5A Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Members of the ARID protein family, including ARID5A, have diverse functions but all appear to play important roles in development, tissue-specific gene expression, and regulation of cell growth.

Synonyms

DAP3-binding cell death enhancer 1; Death ligand signal enhancer; DELE1; DELE; KIAA0141

Gene Name

ARID5A

Gene ID

10865

UniProt

Q03989

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human ARID5A recombinant protein (Position: R55-L594) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Essential for the induction of death receptor-mediated apoptosis through the regulation of caspase activation.

References & Citations

1. Amano, K., Hata, K., Muramatsu, S., Wakabayashi, M., Takigawa, Y., Ono, K., Nakanishi, M., Takashima, R., Kogo, M., Matsuda, A., Nishimura, R., Yoneda, T. Arid5a cooperates with Sox9 to stimulate chondrocyte-specific transcription. Molec. Biol. Cell 22: 1300-1311, 2011. 2. Georgescu, S. P., Li, J. H., Lu, Q., Karas, R. H., Brown, M., Mendelsohn, M. E. Modulator recognition factor 1, an AT-rich interaction domain family member, is a novel corepressor for estrogen receptor alpha. Molec. Endocr. 19: 2491-2501, 2005. 3. Gross, M. B. Personal Communication. Baltimore, Md. 2/26/2015.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

64099 MW

Applications Notes

6

Gene Name Synonym

DAP3 binding cell death enhancer 1

Subcellular Location

Mitochondrion.

Protein Name

DAP3 binding cell death enhancer 1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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