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Anti-Carbonic anhydrase 10/CA10 Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene. This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.

Synonyms

Suppressor of tumorigenicity 7 protein; Protein FAM4A1; Protein HELG; ST7; FAM4A1, HELG, RAY1

Gene Name

CA10

Gene ID

56934

UniProt

Q9NS85

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Carbonic anhydrase 10/CA10 recombinant protein (Position: M1-K328) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed, with highest levels in heart, liver and pancreas. .

Applications

Flow Cytometry

Field of Research

Cancer, Oncoproteins/Suppressors, Tumor Suppressors

Purification

Immunogen affinity purified.

Form

Liquid

Function

May act as a tumor suppressor. .

References & Citations

1. Hewett-Emmett, D., Tashian, R. E. Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families. Molec. Phylogenet. Evol. 5: 50-77, 1996. 2. Kleiderlein, J. J., Nisson, P. E., Jessee, J., Li, W.-B., Becker, K. G., Derby, M. L., Ross, C. A., Margolis, R. L. CCG repeats in cDNAs from human brain. Hum. Genet. 103: 666-673, 1998. Erratum: Hum. Genet. 104: 113 only, 1999. 3. Lovejoy, D. A., Hewett-Emmett, D., Porter, C. A., Cepoi, D., Sheffield, A., Vale, W. W., Tashian, R. E. Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3. Genomics 54: 484-493, 1998.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

67166 MW

Applications Notes

6

Gene Name Synonym

Suppressor of tumorigenicity 7 protein

Subcellular Location

Membrane ; Multi-pass membrane protein .

Protein Name

Suppressor of tumorigenicity 7 protein

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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