Anti-Carbonic anhydrase 10/CA10 Antibody Picoband®

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene. This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene.

1. Hewett-Emmett, D., Tashian, R. E. Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families. Molec. Phylogenet. Evol. 5: 50-77, 1996. 2. Kleiderlein, J. J., Nisson, P. E., Jessee, J., Li, W.-B., Becker, K. G., Derby, M. L., Ross, C. A., Margolis, R. L. CCG repeats in cDNAs from human brain. Hum. Genet. 103: 666-673, 1998. Erratum: Hum. Genet. 104: 113 only, 1999. 3. Lovejoy, D. A., Hewett-Emmett, D., Porter, C. A., Cepoi, D., Sheffield, A., Vale, W. W., Tashian, R. E. Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3. Genomics 54: 484-493, 1998.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.