Anti-NDUFB5 Antibody Picoband® Fluoro550 Conjugated
Product Specifications
Background
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa is a protein that in humans is encoded by the NDUFB5 gene. The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I) . Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms
Neutrophil defensin 1; Defensin, alpha 1; HNP-1; HP-1; HP1; HP 1-56; Neutrophil defensin 2; HNP-2; HP-2; HP2; DEFA1; DEF1, DEFA2, MRS; DEFA1B
Gene Name
NDUFB5
Gene ID
4711
UniProt
O43674
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human NDUFB5 recombinant protein (Position: F32-N189) .
Clonality
Polyclonal
Tissue Specificity
Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
Applications
Flow Cytometry
Field of Research
Defensin, Human Protein, Immunology, Innate Immunity, Macrophage/Inflammation, Microbiology, Protein, Secreted Molecules
Purification
Immunogen affinity purified.
Form
Liquid
Function
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. .
References & Citations
1. Ton, C., Hwang, D. M., Dempsey, A. A., Liew, C.-C. Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits. Biochem. Biophys. Res. Commun. 241: 589-594, 1997.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Calculated Molecular Weight
10201 MW
Applications Notes
6
Gene Name Synonym
Neutrophil defensin 1
Subcellular Location
Secreted.
Protein Name
Neutrophil defensin 1
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Mouse Monoclonal PSMA/FOLH1/NAALADase I Antibody (FOLH1/2354) [Allophycocyanin]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NBP3-08385APC 0.1 mL
Mouse Monoclonal PSMA/FOLH1/NAALADase I Antibody (FOLH1/2354) [Allophycocyanin]
Sign In for Pricing
View Details