Anti-SLC14A1/UTE Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Urea transporter 1 is a protein that in humans is encoded by the SLC14A1 gene. The SLC14A1 codes for a urea transporter (UTB) that is expressed in erythrocytes and kidney. SLC14A2 and SLC14A1 constitute solute carrier family 14. UTB proteins constitute the Kidd antigen system.

Synonyms

Meiotic recombination protein REC8 homolog; Cohesin Rec8p; REC8; REC8L1

Gene Name

Slc14a1

Gene ID

108052

UniProt

Q8VHL0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human SCEL, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Tissue Specificity

Expressed in testis and thymus. Expressed in the B-cell lines WI-L2-NS and Namalwa.

Applications

Flow Cytometry

Field of Research

Vasculature

Purification

Immunogen affinity purified.

Form

Liquid

Function

Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 2/16/2016. 2. Lucien, N., Chiaroni, J., Cartron, J.-P., Bailly, P. Partial deletion in the JK locus causing a Jk (null) phenotype. Blood 99: 1079-1081, 2002. 3. Lucien, N., Sidoux-Walter, F., Olives, B., Moulds, J., Le Pennec, P.-Y., Cartron, J.-P., Bailly, P. Characterization of the gene encoding the human Kidd blood group/urea transporter protein: evidence for splice site mutations in Jk-null individuals. J. Biol. Chem. 273: 12973-12980, 1998.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

56903 MW

Applications Notes

Gene Name Synonym

REC8 meiotic recombination protein

Subcellular Location

Nucleus. Chromosome. Centromere.

Protein Name

Vesicular acetylcholine transporter

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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Anti-SLC14A1/UTE Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Cross Reactivity

Immunogen

Clonality

Tissue Specificity

Applications

Field of Research

Purification

Form

Function

References & Citations

Storage Conditions

Calculated Molecular Weight

Applications Notes

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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