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Anti-Tmem255b Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

FAM70B (family with sequence similarity 70, member B) is a 326 amino acid membrane protein that belongs to the FAM70 family. The gene that encodes FAM70B maps to human chromosome 13, which contains around 114 million base pairs and encodes roughly 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Synonyms

Placenta-specific protein 9; PLAC9

Gene Name

Tmem255b

Gene ID

272465

UniProt

Q5FW56

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse Tmem255b recombinant protein (Position: Q196-L240) .

Clonality

Polyclonal

Tissue Specificity

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Applications

Flow Cytometry

Field of Research

Cell Biology, Cell Type Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Form

Liquid

Function

Involved in cellular response to oxidative stress.

References & Citations

1. Human Gene Database, GeneCards. TMEM255B Gene. Weizman Institute of Science. GeneCards. Retrieved 19 February 2017.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

24145 MW

Applications Notes

6

Gene Name Synonym

Placenta specific 9

Subcellular Location

Secreted.

Protein Name

Transmembrane protein 240

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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