What sizes are available for Anti-Inhibin alpha/INHA Antibody Picoband® Fluoro647 Conjugated?

Anti-Inhibin alpha/INHA Antibody Picoband® Fluoro647 Conjugated is available in the following size(s): 100 µg/Vial.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Anti-Inhibin alpha/INHA Antibody Picoband® Fluoro647 Conjugated

Q: What is the catalog number for Anti-Inhibin alpha/INHA Antibody Picoband® Fluoro647 Conjugated?

The catalog number for Anti-Inhibin alpha/INHA Antibody Picoband® Fluoro647 Conjugated is A02413-3-Fluoro647.

Selected Variant

A02413-3-Fluoro647

Size: 100 µg/Vial

Product Specifications

Background

Inhibin, alpha, also known as INHA, is a protein which in humans is encoded by the INHA gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients.

Synonyms

Bromodomain-containing protein 2; O27.1.1; Really interesting new gene 3 protein; BRD2; KIAA9001; RING3

Gene Name

INHA

Gene ID

3623

UniProt

P05111

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Inhibin alpha/INHA recombinant protein (Position: E254-I366) .

Clonality

Polyclonal

Tissue Specificity

Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development.

Applications

Flow Cytometry

Field of Research

Cytoplasmic, Signaling Pathways, Stem Cells

Purification

Immunogen affinity purified.

Form

Liquid

Function

May play a role in spermatogenesis or folliculogenesis (By similarity) . Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.

References & Citations

1. Arunachalam, B., Phan, U. T., Geuze, H. J., Cresswell, P. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT) . Proc. Nat. Acad. Sci. 97: 745-750, 2000. 2. Maric, M., Arunachalam, B., Phan, U. T., Dong, C., Garrett, W. S., Cannon, K. S., Alfonso, C., Karlsson, L., Flavell, R. A., Cressell, P. Defective antigen processing in GILT-free mice. Science 294: 1361-1365, 2001. 3. Phan, U. T., Arunachalam, B., Cresswell, P. Gamma-interferon-inducible lysosomal thiol reductase (GILT) : maturation, activity, and mechanism of action. J. Biol. Chem. 275: 25907-25914, 2000.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

78948 MW

Applications Notes

Gene Name Synonym

Bromodomain containing 2

Subcellular Location

Nucleus.

Protein Name

Segment polarity protein dishevelled homolog DVL-2

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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