Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Inhibin alpha/INHA Antibody Picoband®

Boster Bio Anti-Inhibin alpha/INHA Antibody Picoband® catalog # A02413-3. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Inhibin, alpha, also known as INHA, is a protein which in humans is encoded by the INHA gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients.

Synonyms

Bromodomain-containing protein 2; O27.1.1; Really interesting new gene 3 protein; BRD2; KIAA9001; RING3

Gene Name

INHA

Gene ID

3623

UniProt

P05111

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Inhibin alpha/INHA recombinant protein (Position: E254-I366) .

Clonality

Polyclonal

Tissue Specificity

Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Cytoplasmic, Signaling Pathways, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May play a role in spermatogenesis or folliculogenesis (By similarity) . Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.

References & Citations

1. Arunachalam, B., Phan, U. T., Geuze, H. J., Cresswell, P. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT) . Proc. Nat. Acad. Sci. 97: 745-750, 2000. 2. Maric, M., Arunachalam, B., Phan, U. T., Dong, C., Garrett, W. S., Cannon, K. S., Alfonso, C., Karlsson, L., Flavell, R. A., Cressell, P. Defective antigen processing in GILT-free mice. Science 294: 1361-1365, 2001. 3. Phan, U. T., Arunachalam, B., Cresswell, P. Gamma-interferon-inducible lysosomal thiol reductase (GILT) : maturation, activity, and mechanism of action. J. Biol. Chem. 275: 25907-25914, 2000.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

78948 MW

Observed Molecular Weight

45 kDa

Applications Notes

6

Gene Name Synonym

Bromodomain containing 2

Subcellular Location

Nucleus.

Protein Name

Segment polarity protein dishevelled homolog DVL-2

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Active Tryptase (TPS)
MBS2162343-01 0.01 mg

Active Tryptase (TPS)

Sign In for Pricing
View Details
Active Tryptase (TPS)
MBS2162343-02 0.05 mg

Active Tryptase (TPS)

Sign In for Pricing
View Details
Active Tryptase (TPS)
MBS2162343-03 0.1 mg

Active Tryptase (TPS)

Sign In for Pricing
View Details
Active Tryptase (TPS)
MBS2162343-04 0.2 mg

Active Tryptase (TPS)

Sign In for Pricing
View Details
Active Tryptase (TPS)
MBS2162343-05 0.5 mg

Active Tryptase (TPS)

Sign In for Pricing
View Details
Active Tryptase (TPS)
MBS2162343-06 1 mg

Active Tryptase (TPS)

Sign In for Pricing
View Details