Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Clathrin heavy chain/CLTC Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

Clathrin heavy chain 1 is a protein that in humans is encoded by the CLTC gene. Clathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

Synonyms

Tumor necrosis factor receptor superfamily member 18; Glucocorticoid-induced TNFR-related protein; CD357; Tnfrsf18; Gitr

Gene Name

CLTC

Gene ID

1213

UniProt

Q00610

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Clathrin heavy chain/CLTC recombinant protein (Position: R967-Q1668) .

Clonality

Polyclonal

Tissue Specificity

Detected in thymus and in activated splenocytes.

Applications

Flow Cytometry

Field of Research

Adaptive Immunity, Cancer, Cytokines, Growth Factors, Growth Factors/Hormones, Immunology, Innate Immunity, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

References & Citations

1. Argani, P., Lui, M. Y., Couturier, J., Bouvier, R., Fournet, J.-C., Ladanyi, M. A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t (X;17) (p11.2; q23) . Oncogene 22: 5374-5378, 2003. 2. Cools, J., Wlodarska, I., Somers, R., Mentens, N., Pedeutour, F., Maes, B., De Wolf-Peeters, C., Pauwels, P., Hagemeijer, A., Marynen, P. Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor. Genes Chromosomes Cancer 34: 354-362, 2002. 3. Deborde, S., Perret, E., Gravotta, D., Deora, A., Salvarezza, S., Schreiner, R., Rodriguez-Boulan, E. Clathrin is a key regulator of basolateral polarity. Nature 452: 719-723, 2008.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

26000 MW

Applications Notes

6

Gene Name Synonym

Tumor necrosis factor receptor superfamily, member 18

Subcellular Location

Cell membrane. Single-pass type I membrane protein. Secreted.

Protein Name

Transcription factor E2F3

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Gm3448 (NM_001123367) Mouse Tagged Lenti ORF Clone
MR212275L3 10 µg

Gm3448 (NM_001123367) Mouse Tagged Lenti ORF Clone

Sign In for Pricing
View Details
TAS2R10 Polyclonal Antibody
MBS9432439-01 0.05 mL

TAS2R10 Polyclonal Antibody

Sign In for Pricing
View Details
TAS2R10 Polyclonal Antibody
MBS9432439-02 0.1 mL

TAS2R10 Polyclonal Antibody

Sign In for Pricing
View Details
TAS2R10 Polyclonal Antibody
MBS9432439-03 5x 0.1 mL

TAS2R10 Polyclonal Antibody

Sign In for Pricing
View Details
Recombinant p57 Kip2 Antibody
RC-15373-01 50 μL

Recombinant p57 Kip2 Antibody

Sign In for Pricing
View Details
Recombinant p57 Kip2 Antibody
RC-15373-02 100 µL

Recombinant p57 Kip2 Antibody

Sign In for Pricing
View Details