What sizes are available for Anti-Claudin 5/CLDN5 Antibody Fluoro550 Conjugated?

Anti-Claudin 5/CLDN5 Antibody Fluoro550 Conjugated is available in the following size(s): 100 µg/Vial.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

Anti-Claudin 5/CLDN5 Antibody Fluoro550 Conjugated

Q: What is the catalog number for Anti-Claudin 5/CLDN5 Antibody Fluoro550 Conjugated?

The catalog number for Anti-Claudin 5/CLDN5 Antibody Fluoro550 Conjugated is A03260-3-Fluoro550.

Q: Is Anti-Claudin 5/CLDN5 Antibody Fluoro550 Conjugated in stock?

Anti-Claudin 5/CLDN5 Antibody Fluoro550 Conjugated is currently made to order / not held in immediate stock. Contact us for lead time.

Selected Variant

A03260-3-Fluoro550

Size: 100 µg/Vial

Product Specifications

Background

Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Synonyms

Thrombospondin-2; THBS2; TSP2

Gene Name

CLDN5

Gene ID

7122

UniProt

O00501

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5/CLDN5, which shares 95% and 90% amino acid (aa) sequence identity with mouse and rat Claudin 5/CLDN5, respectively.

Clonality

Polyclonal

Tissue Specificity

High expression in invertebral disk tissue.

Applications

Flow Cytometry

Field of Research

Calcium Signaling, Calmodulin Pathway, Cardiovascular, Hypertrophy, Neuroscience, Neurotransmission, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Form

Liquid

Function

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.

References & Citations

1. Sirotkin, H., Morrow, B., Saint-Jore, B., Puech, A., Das Gupta, R., Patanjali, S. R., Skoultchi, A., Weissman, S. M., Kucherlapati, R. Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. 2. Peacock RE, Keen TJ, Inglehearn CF (Mar 1998) . Analysis of a human gene homologous to rat ventral prostate.1 protein. Genomics 46 (3) : 443–9. 3. Entrez Gene: CLDN5 claudin 5 (transmembrane protein deleted in velocardiofacial syndrome)

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Applications Notes

Gene Name Synonym

Thrombospondin 2

Subcellular Location

Synapse. Postsynaptic density. Dendritic spine. Dendrite.

Isotype

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Price

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