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Anti-LY6C Antibody Picoband® Fluoro594 Conjugated

Product Specifications

Background

Ly6C is a murine cell-surface antigen expressed by plasma cells, subsets of myeloid cells and many T cells, including memory T cells.

Synonyms

NADH-ubiquinone oxidoreductase chain 2; NADH dehydrogenase subunit 2; Mtnd2; mt-Nd2; Nd2

Gene Name

Ly6c1/2

Gene ID

17067/100041546

UniProt

P0CW02

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse LY6C recombinant protein (Position: L27-G109) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

Flow Cytometry

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Form

Liquid

Function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

References & Citations

1. Arno Hänninen, Mikael Maksimow, Catharina Alam, David J Morgan, Sirpa Jalkanen. Ly6C Supports Preferential Homing of Central Memory CD8+ T Cells Into Lymph Nodes. Eur J Immunol. 2011 Mar;41 (3) :634-44. doi: 10.1002/eji.201040760. Epub 2011 Feb 10.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Calculated Molecular Weight

14377 MW

Applications Notes

6

Gene Name Synonym

NADH dehydrogenase 2, mitochondrial

Subcellular Location

Mitochondrion inner membrane. Multi-pass membrane protein.

Protein Name

Lymphocyte antigen 6A-2/6E-1

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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