Anti-CD69 Antibody Picoband® Fluoro594 Conjugated
Product Specifications
Background
This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets.
Synonyms
Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; Afp
Gene Name
CD69
Gene ID
969
UniProt
Q07108
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human CD69 recombinant protein (Position: T101-E148) .
Clonality
Polyclonal
Tissue Specificity
Plasma.
Applications
Flow Cytometry
Field of Research
Cancer, Cardiovascular, Developmental Biology, Organogenesis, Serum Proteins, Tumor Antigens, Tumor Biomarkers
Purification
Immunogen affinity purified.
Form
Liquid
Function
Binds estrogens, fatty acids and metals.
References & Citations
1. Cambiaggi, C., Scupoli, M. T., Cestari, T., Gerosa, F., Carra, G., Tridente, G., Accolla, R. S. Constitutive expression of CD69 in interspecies T-cell hybrids and locus assignment to human chromosome 12. Immunogenetics 36: 117-120, 1992. 2. Esplugues, E., Sancho, D., Vega-Ramos, J., Martinez-A, C., Syrbe, U., Hamann, A., Engel, P., Sanchez-Madrid, F., Lauzurica, P. Enhanced antitumor immunity in mice deficient in CD69. J. Exp. Med. 197: 1093-1106, 2003. 3. Sancho, D., Gomez, M., Viedma, F., Esplugues, E., Gordon-Alonso, M., Garcia-Lopez, M. A., de la Fuente, H., Martinez-A, C., Lauzurica, P., Sanchez-Madrid, F. CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis. J. Clin. Invest. 112: 872-882, 2003.
Storage Conditions
At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Applications Notes
6
Gene Name Synonym
Alpha-fetoprotein
Subcellular Location
Secreted.
Isotype
Rabbit IgG
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
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