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Anti-GLUT10/SLC2A10 Antibody Picoband®

Boster Bio Anti-GLUT10/SLC2A10 Antibody Picoband® catalog # A06461-2. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Solute carrier family 2, facilitated glucose transporter member 10 is a protein that in humans is encoded by the SLC2A10 gene. It is mapped to 20q13.12. This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.

Synonyms

Solute carrier family 2, facilitated glucose transporter member 10; Glucose transporter type 10; GLUT-10; SLC2A10; GLUT10

Gene Name

SLC2A10

Gene ID

81031

UniProt

O95528

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human GLUT10/SLC2A10 recombinant protein (Position: A32-Q511) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed; highest levels in liver and pancreas.

Applications

WB, ELISA

Field of Research

Neural Signal Transduction, Neurology Process, Neuroscience

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Facilitative glucose transporter required for the development of the cardiovascular system.

References & Citations

1. Faiyaz-Ul-Haque, M., Zaidi, S. H. E., Wahab, A. A., Eltohami, A., Al-Mureikhi, M. S., Al-Thani, G., Peltekova, V. D., Tsui, L.-C., Teebi, A. S. Identification of a pSer81Arg encoding mutation in SLC2A10 gene of arterial tortuosity syndrome patients from 10 Qatari families. (Letter) Clin. Genet. 74: 189-193, 2008. 2. Lee, Y.-C., Huang, H.-Y., Chang, C.-J., Cheng, C.-H., Chen, Y.-T. Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome. Hum. Molec. Genet. 19: 3721-3733, 2010. 3. McVie-Wylie, A. J., Lamson, D. R., Chen, Y. T. Molecular cloning of a novel member of the GLUT family of transporters, SLC2A10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility. Genomics 72: 113-117, 2001.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

67 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Solute carrier family 2 member 10

Subcellular Location

Endomembrane system. Multi-pass membrane protein. Perinuclear region.

Isotype

Rabbit IgG

Contents

243

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