Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-RBPMS Antibody Picoband®

Boster Bio Anti-RBPMS Antibody catalog # A07130-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

RNA-binding protein with multiple splicing is a protein that in humans is encoded by the RBPMS gene. It is mapped to 8p12. This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

RNA-binding protein with multiple splicing; RBP-MS; Heart and RRM expressed sequence; Hermes; RBPMS; HERMES

Gene Name

RBPMS

Gene ID

11030

UniProt

Q93062

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RBPMS recombinant protein (Position: K6-C196) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed, at various levels depending on the isoform and the tissue.

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Cancer, DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, Translation, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly (A) RNA.

References & Citations

1. Lim, J., Hao, T., Shaw, C., Patel, A. J., Szabo, G., Rual, J.-F., Fisk, C. J., Li, N., Smolyar, A., Hill, D. E., Barabasi, A.-L., Vidal, M., Zoghbi, H. Y. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell 125: 801-814, 2006. 2. Shimamoto, A., Kitao, S., Ichikawa, K., Suzuki, N., Yamabe, Y., Imamura, O., Tokutake, Y., Satoh, M., Matsumoto, T., Kuromitsu, J., Kataoka, H., Sugawara, K., Sugawara, M., Sugimoto, M., Goto, M., Furuichi, Y. A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs. Proc. Nat. Acad. Sci. 93: 10913-10917, 1996.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

22 kDa

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

RNA binding protein, mRNA processing factor

Subcellular Location

Nucleus. Cytoplasm. P-body.

Isotype

Rabbit IgG

Contents

243

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse SLC22A7 shRNA Plasmid
abx979891-01 150 µg

Mouse SLC22A7 shRNA Plasmid

Ask
View Details
Mouse SLC22A7 shRNA Plasmid
abx979891-02 300 µg

Mouse SLC22A7 shRNA Plasmid

Ask
View Details
Simport Slidefolder Opaque Lid
M75220WOP 10 / PCK

Simport Slidefolder Opaque Lid

Ask
View Details
Rpp30 shRNA (h) Lentiviral Particles
sc-38352-V 200 µL

Rpp30 shRNA (h) Lentiviral Particles

Ask
View Details
Recombinant Lactobacillus johnsonii 10 kDa chaperonin (groS)
MBS1433970-01 0.02 mg (E-Coli)

Recombinant Lactobacillus johnsonii 10 kDa chaperonin (groS)

Ask
View Details
Recombinant Lactobacillus johnsonii 10 kDa chaperonin (groS)
MBS1433970-02 0.1 mg (E-Coli)

Recombinant Lactobacillus johnsonii 10 kDa chaperonin (groS)

Ask
View Details