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Anti-FRMD6/Willin Antibody Picoband® Fluoro488 Conjugated

Product Specifications

Background

FERM domain-containing protein 6 is a protein that in humans is encoded by the FRMD6 gene. It is mapped to 14q22.1.

Synonyms

FERM domain-containing protein 6; Willin; FRMD6; C14orf31

Gene Name

FRMD6

Gene ID

122786

UniProt

Q96NE9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human FRMD6/Willin recombinant protein (Position: M1-E95) .

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

Applications

Flow Cytometry

Field of Research

Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Form

Liquid

Function

Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division.

References & Citations

1. Gunn-Moore, F. J., Welsh, G. I., Herron, L. R., Brannigan, F., Venkateswarlu, K., Gillespie, S., Brandwein-Gensler, M., Madan, R., Tavare, J. M., Brophy, P. J., Prystowsky, M. B., Guild, S. A novel 4.1 ezrin radixin moesin (FERM) -containing protein, 'Willin.' FEBS Lett. 579: 5089-5094, 2005. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 3/23/2012.

Storage Conditions

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Specificity

No cross reactivity with other proteins.

Applications Notes

6

Gene Name Synonym

FERM domain containing 6

Subcellular Location

Cell membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm.

Isotype

Rabbit IgG

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

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